快速链接

生命科学技术学院(生物医药研究院)基因工程药物国家工程研究中心暨南大学广东省生物工程药物重点实验室

 

题目：Post-transcriptional gene regulation and    deregulation in human diseases
报告人：陈炜教授
陈炜教授个人简介：德国MAX DELBRÜCK分子医学中心
Dr. Chen obtained his Ph.D. degree from Max-Planck-Institute for Molecular Genetics in 2006. He trained in human molecular genetics and bioinformatics. Between 2007 and 2008, he stayed at the same institute and led a research group. His group developed one of the first experimental and data analysis pipelines for Illumina/Solexa sequencing. At 2009, he moved to the newly established Berlin Institute for Medical Systems Biology at Max-Delbrueck-Center for Molecular Medicine, where he led the genomics platform. His lab has been developing various genomic assays based on the novel sequencing technology. The research interest of his lab is to understand the mechanisms underlying post-transcriptional gene regulation and their important role in causing human diseases
  1. Wang, Y., Gogol-Döring, A., Hu, H., Fröhler, S., Ma, Y., Jens, M., Maaskola, J., Murakawa, Y., Quedenau, C., Landthaler, M., Kalscheuer, V., Wieczorek, D., Wang, Y., Hu, Y. and Chen, W (2013) Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation. EMBO Mol Med. 2013 doi: 10.1002/emmm.201302663
  2. Sun W, You X, Gogol-Döring A, He H, Kise Y, Sohn M, Chen T, Klebes A, Schmucker D, Chen W (2013) Ultra-deep profiling of alternatively spliced Drosophila Dscam isoforms by circularization-assisted multi-segment sequencing. EMBO J. 2013 Jun 21. doi: 10.1038/emboj.2013.144. [Epub ahead of print]
  3. Schwanhäusser B, Busse D, Li N, Dittmar G, Schuchhardt J, Wolf J*, Chen W*, Selbach M*. (2011) Global quantification of mammalian gene expression control Nature. 2011 May 19;473(7347):337-42
  4. Adamidi C, Wang Y, Gruen D, Mastrobuoni G, You X, Tolle D, Dodt M, Mackowiak SD, Gogol-Doering A, Oenal P, Rybak A, Ross E, Alvarado AS, Kempa S*, Dieterich C*, Rajewsky N*, Chen W * (2011) De novo assembly and validation of planaria transcriptome by massive parallel sequencing and shotgun proteomics. Genome Res 21(7):1193-200
主持人：洪岸教授
时 间：2014年5月12日（星期一）下午3：00
地 点：暨南大学第二理工楼701会议室
欢 迎 感 兴 趣 的 师 生 参加！