题目：New Clinical Information and Physician Prescribing: How Do Pediatric Labeling Changes Affect Prescribing to Children?

报告人：尹妮娜

时间：2016年11月25日下午13:30-15:00

地点：暨南大学中惠楼106B

主办方：暨南大学经济与社会研究院

报告人简介：

尹妮娜，中央财经大学人力资本与劳动经济研究中心助理教授，2013年毕业于图卢兹经济学院，获经济学博士。2013-2015年，在杜兰大学从事博士后研究。主要研究方向为卫生经济学，实证产业组织，和创新与知识产权。

摘要：

This paper investigates the impact of pediatric clinical studies and labeling changes, induced by 1997 pediatric exclusivity provision, on the physician's prescribing of pediatric drugs. With unique handly-collected medical information data (about labeling changes and scientific publications about the clinical studies) and NAMCS prescribing data, by adopting DID strategy, we compare prescribing for children and adults in response to different types of labeling changes. Our results indicate that physicians' responsiveness to the new scientific information is not symmetric: Physician prescribing behavior shifts in response to negative clinical trial outcomes, but unaffected by positive labeling changes. It suggests that new negative information included in a drug's label can lead physicians to reduce previous patterns of inefficient off-label prescribing while positive information does not alter previously established patterns of pediatric prescribing. Evidences suggest that the promotion and the dissemination of scientific publications have strong associations with physician prescribing.